Since the most common causes are the normal monthly hormonal fluctuations of the female cycle and pregnancy, spider veins occur most often in women, and they often first appear during pregnancy. Other contributing factors include injuries, medications that affect hormones, and a family history of spider veins. Although it is less common, men can develop spider veins as well. The condition usually appears after age 30, although it can sometimes develop as early as the teen years. Spider veins, or “starbursts,” are so named because the series of veins often radiates out from a central point, reminiscent of the shape of a spider. They may also appear as fine, separate lines, a web-like maze, or as “branches” from a single “tree trunk.” They can develop on any part of the body, including the face, but most often appear on the thighs, calves, or ankles. Spider veins are caused by abnormal blood flow and weakening of the blood vessel wall in the affected veins. Any condition or activity that puts pressure on the veins -- such as gaining weight, and sitting or standing for long periods of time -- can contribute to their development. While unsightliness is the most common reason for removal, spider veins may also be removed to alleviate problems with restless legs, aching, burning, and/or cramps. Spider veins are most often treated with sclerotherapy, in which a saline or chemical solution that is injected into the vein, irritating the lining and causing the vein to collapse and disappear. In some cases, laser treatment may be used either alone or in combination with sclerotherapy. If you are considering sclerotherapy, the following information will provide you with a good introduction to the procedure. For more detailed information about how this procedure may help you, we recommend that you consult a dermatologist who is board certified or has completed a residency program that includes instruction in this procedure.